Software


R/DCLEAR
R/DCLEAR is an R package for Distance based Cell LinEAge Reconstruction(DCLEAR). These codes are created during the participation of Cell Lineage Reconstruction DREAM challenge.

R/DrImpute
R codes for imputing dropout events. Many statistical methods in cell type identification, visualization and lineage reconstruction do not account for dropout events ('PCAreduce', 'SC3', 'PCA', 't-SNE', 'Monocle', 'TSCAN', etc). 'DrImpute' can improve the performance of such software by imputing dropout events.

R/aSPU
R codes for the (adaptive) Sum of Powered Score ('SPU' and 'aSPU') tests, inverse variance weighted Sum of Powered score ('SPUw' and 'aSPUw') tests and gene-based and some pathway based association tests (Pathway based Sum of Powered Score tests ('SPUpath'), adaptive 'SPUpath' ('aSPUpath') test, 'GEEaSPU' test for multiple traits - single 'SNP' (single-nucleotide-polymorphism) association in generalized estimation equations, 'MTaSPUs' test for multiple traits - single 'SNP' association with Genome Wide Association Studies ('GWAS') summary statistics, Gene-based Association Test that uses an extended Simes procedure ('GATES'), Hybrid Set-based Test ('HYST') and extended version of 'GATES' test for pathway-based association testing ('GATES-Simes'). ). The tests can be used with genetic and other data sets with covariates. The response variable is binary or quantitative. Summary; (1) Single trait-'SNP' set association with individual-level data ('aSPU', 'aSPUw'), (2) Single trait-'SNP' set association with summary statistics ('aSPUs'), (3) Single trait-pathway association with individual-level data ('aSPUpath'), (4) Single trait-pathway association with summary statistics ('aSPUsPath'), (5) Multiple traits-single 'SNP' association with individual-level data ('GEEaSPU'), (6) Multiple traits- single SNP association with summary statistics ('MTaSPUs'), (7) Multiple traits-`SNP' set association with summary statistics(`MTaSPUsSet'), (8) Multiple traits-pathway association with summary statistics(`MTaSPUsSetPath').

R/funqtl
An R package with add-on functions for the R/qtl package to deal with function valued trait on QTL mapping.

R/xoi
Tools for analyzing crossover interference. Assisted Karl Broman to develop the package.

R/APCP
An R pacakage that plots Andrews type Parallel Coordinate Plot


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